DIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg

TABLETORALCapricorn Pharma Inc.NDC: 66007-212Updated: Mar 2026

Active Ingredient

DIPHENHYDRAMINE HYDROCHLORIDE — 12.5 mg

Inactive Ingredients (Fillers)

⚠️ 4 ingredients flagged as common allergens

Crospovidone

⚠️ Yes — Povidone

Disintegrant

A cross-linked form of povidone used as a superdisintegrant. Same polymer allergy concern as povidone.

Mannitol

⚠️ Yes — Mannitol

Filler/Sweetener

A sugar alcohol used as a sweetener and bulking agent. Can cause osmotic diarrhea in sensitive individuals.

Modified Corn Starch (1-octenyl Succinic Anhydride)

⚠️ Yes — Corn

Corn starch and pregelatinized starch are used as binders, disintegrants, and fillers in tablets and capsules.

Sodium Lauryl Sulfate

⚠️ Yes — Surfactant

Wetting Agent

A surfactant used to improve drug dissolution. Can cause skin irritation in some individuals.

Ammonia Solution

pH Adjuster

Anhydrous Citric Acid

pH Adjuster/Buffer

Dibasic Calcium Phosphate Dihydrate

Filler/Binder

Ethylcellulose

Coating/Binder

Glyceryl Mono- And Dicaprylocaprate

Emulsifier/Penetration Enhancer

Magnesium Stearate

Lubricant

Maltodextrin

Filler/Binder

Methacrylic Acid - Ethyl Acrylate Copolymer (1:1) Type A

Enteric Coating

Microcrystalline Cellulose

Filler/Binder

Oleic Acid

Surfactant/Stabilizer

Silicon Dioxide

Glidant

Sodium Starch Glycolate Type A

Disintegrant

Sucralose

Sweetener

Talc

Glidant/Lubricant

Triacetin

Plasticizer

Ingredient	Purpose	Common Allergen?	Description
Crospovidone	Disintegrant	⚠️ Yes — Povidone	A cross-linked form of povidone used as a superdisintegrant. Same polymer allergy concern as povidone.
Mannitol	Filler/Sweetener	⚠️ Yes — Mannitol	A sugar alcohol used as a sweetener and bulking agent. Can cause osmotic diarrhea in sensitive individuals.
Modified Corn Starch (1-octenyl Succinic Anhydride)	—	⚠️ Yes — Corn	Corn starch and pregelatinized starch are used as binders, disintegrants, and fillers in tablets and capsules.
Sodium Lauryl Sulfate	Wetting Agent	⚠️ Yes — Surfactant	A surfactant used to improve drug dissolution. Can cause skin irritation in some individuals.
Ammonia Solution	pH Adjuster	No	Dilute ammonia used to adjust pH in pharmaceutical formulations. Present in trace amounts in the final product.
Anhydrous Citric Acid	pH Adjuster/Buffer	No	Water-free citric acid used to adjust pH and enhance drug stability. Typically derived from fermentation of corn sugar.
Dibasic Calcium Phosphate Dihydrate	Filler/Binder	No	A hydrated calcium phosphate salt used as a filler and binder in tablets. Also provides a source of calcium.
Ethylcellulose	Coating/Binder	No	A cellulose derivative used for sustained-release coatings and as a binder. Plant-derived and water-insoluble.
Glyceryl Mono- And Dicaprylocaprate	Emulsifier/Penetration Enhancer	No	Mixed glyceride esters used as emulsifiers and to enhance drug absorption through the skin.
Magnesium Stearate	Lubricant	No	A lubricant that prevents ingredients from sticking to manufacturing equipment.
Maltodextrin	Filler/Binder	No	A starch-derived carbohydrate used as a filler, binder, and coating agent. Typically derived from corn — may be relevant for corn-sensitive individuals.
Methacrylic Acid - Ethyl Acrylate Copolymer (1:1) Type A	Enteric Coating	No	A pH-sensitive polymer (Eudragit L 100-55) that dissolves above pH 5.5, used as an enteric coating to protect tablets from stomach acid.
Microcrystalline Cellulose	Filler/Binder	No	Refined wood pulp used as a filler and binder. Generally inert and well-tolerated.
Oleic Acid	Surfactant/Stabilizer	No	Surfactant in MDI formulations that helps drug particles stay suspended in the propellant.
Silicon Dioxide	Glidant	No	A mineral (silica) used to improve powder flow during tablet manufacturing. Also called colloidal silicon dioxide.
Sodium Starch Glycolate Type A	Disintegrant	No	A modified starch (typically potato-derived) that swells rapidly in water, helping tablets break apart for faster drug release.
Sucralose	Sweetener	No	A non-caloric artificial sweetener approximately 600 times sweeter than sugar. Used to improve taste in oral medications.
Talc	Glidant/Lubricant	No	A mineral used to improve powder flow in manufacturing.
Triacetin	Plasticizer	No	Glyceryl triacetate. A plasticizer used in film coatings to make them flexible and prevent cracking.

Exclusion Groups

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

🌾Gluten 🔴Alpha-Gal Syndrome 🍬Polyols (GI)🌱Not Vegan ☪️Halal Concern ✡️Kosher Concern 🥦Not Vegetarian

Dietary & Safety Information

Cross-Contamination Risk (source-dependent)

3 ingredients may have cross-contamination risk with gluten (source-dependent):

Maltodextrin — May contain (source-dependent)
Modified Corn Starch (1-octenyl Succinic Anhydride) — May contain (source-dependent)
Sodium Starch Glycolate Type A — May contain (source-dependent)

Alpha-Gal Syndrome Risk

1 ingredient may contain mammalian-derived components:

Magnesium Stearate(Possible — Stearates can be plant- or animal-derived (verify source).)