Diphenhydramine Hydrochloride 25 mg

TABLET, COATEDORALBonita Pharmaceuticals LLCNDC: 53598-004Updated: Mar 2026

Active Ingredient

⚠️ 2 ingredients flagged as common allergens

Polyethylene Glycol

⚠️ Yes — PEG

Coating/Plasticizer

A polymer used in coatings and as a plasticizer. Rare but documented allergic reactions, including anaphylaxis in sensitive individuals.

Propylene Glycol

⚠️ Yes — Propylene Glycol

Solvent/Humectant

An organic compound used as a solvent and humectant. Can cause contact dermatitis in sensitive individuals.

Croscarmellose Sodium

Disintegrant

D&C Red No. 27

Colorant

Dibasic Calcium Phosphate Dihydrate

Filler/Binder

Hypromellose

Coating

Magnesium Stearate

Lubricant

Microcrystalline Cellulose

Filler/Binder

Silicon Dioxide

Glidant

Stearic Acid

Lubricant

Titanium Dioxide

Colorant/Opacifier

Ingredient	Purpose	Common Allergen?	Description
Polyethylene Glycol	Coating/Plasticizer	⚠️ Yes — PEG	A polymer used in coatings and as a plasticizer. Rare but documented allergic reactions, including anaphylaxis in sensitive individuals.
Propylene Glycol	Solvent/Humectant	⚠️ Yes — Propylene Glycol	An organic compound used as a solvent and humectant. Can cause contact dermatitis in sensitive individuals.
Croscarmellose Sodium	Disintegrant	No	A chemically modified cellulose derivative that helps tablets dissolve quickly.
D&C Red No. 27	Colorant	No	A synthetic red dye used in medications and cosmetics. May cause reactions in dye-sensitive individuals.
Dibasic Calcium Phosphate Dihydrate	Filler/Binder	No	A hydrated calcium phosphate salt used as a filler and binder in tablets. Also provides a source of calcium.
Hypromellose	Coating	No	A semisynthetic polymer used for tablet coating. Derived from cellulose.
Magnesium Stearate	Lubricant	No	A lubricant that prevents ingredients from sticking to manufacturing equipment.
Microcrystalline Cellulose	Filler/Binder	No	Refined wood pulp used as a filler and binder. Generally inert and well-tolerated.
Silicon Dioxide	Glidant	No	A mineral (silica) used to improve powder flow during tablet manufacturing. Also called colloidal silicon dioxide.
Stearic Acid	Lubricant	No	A fatty acid used as a lubricant in tablet manufacturing.
Titanium Dioxide	Colorant/Opacifier	No	A white pigment used for coating opacity. Under regulatory review in some countries.

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

2 ingredients may contain mammalian-derived components:

Magnesium Stearate(Possible — Stearates can be plant- or animal-derived (verify source).)
Stearic Acid(Possible — Stearates can be plant- or animal-derived (verify source).)