Wynzora (Calcipotriene and Betamethasone dipropionate) 50 ug / 64 mg

CREAMTOPICALMC2 Therapeutics LtdNDC: 73499-001Updated: Mar 2026

Active Ingredients

Calcipotriene — 50 ug

Betamethasone dipropionate — 64 mg

Inactive Ingredients (Fillers)

⚠️ 4 ingredients flagged as common allergens

Carbomer Homopolymer Type B (allyl Sucrose Crosslinked)

⚠️ Yes — Sucrose

Thickener/Gelling Agent

Medium-chain Triglycerides

⚠️ Yes — Coconut

Solvent/Vehicle

Poloxamer 407

⚠️ Yes — Poloxamer

Solubilizer/Emulsifier

Polyoxyl 40 Hydrogenated Castor Oil

⚠️ Yes — Castor Oil

Solubilizer/Emulsifier

.alpha.-tocopherol, Dl-

Butylated Hydroxyanisole

Antioxidant

Hamamelis Virginiana Top Water

Skin Conditioner

Isopropyl Alcohol

Solvent/Antiseptic

Isopropyl Myristate

Emollient/Penetration Enhancer

Laureth-4

Mineral Oil

Emollient/Vehicle

Sodium Phosphate, Dibasic, Heptahydrate

Sodium Phosphate, Monobasic, Monohydrate

Trolamine

Emulsifier/pH Adjuster

Ingredient	Purpose	Common Allergen?	Description
Carbomer Homopolymer Type B (allyl Sucrose Crosslinked)	Thickener/Gelling Agent	⚠️ Yes — Sucrose	A sucrose-crosslinked acrylic acid polymer used to create gels for topical formulations.
Medium-chain Triglycerides	Solvent/Vehicle	⚠️ Yes — Coconut	Fatty acid esters derived from coconut or palm kernel oil. Used as a solvent and vehicle in oral and topical formulations. May be relevant for individuals with coconut sensitivity.
Poloxamer 407	Solubilizer/Emulsifier	⚠️ Yes — Poloxamer	A non-ionic block copolymer surfactant (Pluronic F127) used to solubilize drugs and create thermoreversible gels.
Polyoxyl 40 Hydrogenated Castor Oil	Solubilizer/Emulsifier	⚠️ Yes — Castor Oil	A non-ionic surfactant (Cremophor RH 40) derived from castor oil, used to solubilize hydrophobic drugs. Rare hypersensitivity reactions reported.
.alpha.-tocopherol, Dl-	—	No	—
Butylated Hydroxyanisole	Antioxidant	No	BHA. A synthetic antioxidant used to prevent rancidity of fats and oils. Rare contact sensitivity reported.
Hamamelis Virginiana Top Water	Skin Conditioner	No	Witch hazel distillate, a plant-derived astringent used in topical formulations to soothe and tone the skin.
Isopropyl Alcohol	Solvent/Antiseptic	No	Rubbing alcohol. Used as a solvent in topical formulations and as an antiseptic agent.
Isopropyl Myristate	Emollient/Penetration Enhancer	No	A synthetic ester used as an emollient and to enhance penetration of active ingredients through the skin.
Laureth-4	—	No	—
Mineral Oil	Emollient/Vehicle	No	A purified petroleum-derived oil used as an emollient and vehicle in topical formulations and as a lubricant in oral laxatives.
Sodium Phosphate, Dibasic, Heptahydrate	—	No	—
Sodium Phosphate, Monobasic, Monohydrate	—	No	—
Trolamine	Emulsifier/pH Adjuster	No	Triethanolamine. Used as an emulsifier and pH adjuster in topical creams and lotions.

Exclusion Groups

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

🫘Soy 🥜Peanut / Tree Nut

AllergenMaps

Ingredient

Purpose

Common Allergen?

Carbomer Homopolymer Type B (allyl Sucrose Crosslinked)

Thickener/Gelling Agent

⚠️ Yes — Sucrose

Medium-chain Triglycerides

Solvent/Vehicle

⚠️ Yes — Coconut

Poloxamer 407

Solubilizer/Emulsifier

⚠️ Yes — Poloxamer

Polyoxyl 40 Hydrogenated Castor Oil

Solubilizer/Emulsifier

⚠️ Yes — Castor Oil

.alpha.-tocopherol, Dl-

—

Butylated Hydroxyanisole

Antioxidant

Hamamelis Virginiana Top Water

Skin Conditioner

Isopropyl Alcohol

Solvent/Antiseptic

Isopropyl Myristate

Emollient/Penetration Enhancer

Laureth-4

—

Mineral Oil

Emollient/Vehicle

Sodium Phosphate, Dibasic, Heptahydrate

—

Sodium Phosphate, Monobasic, Monohydrate

—

Trolamine

Emulsifier/pH Adjuster