VENLAFAXINE HYDROCHLORIDE (venlafaxine) 225 mg

TABLET, EXTENDED RELEASEORALXLCare Pharmaceuticals, Inc.NDC: 72865-200Updated: Mar 2026

Active Ingredient

VENLAFAXINE HYDROCHLORIDE — 225 mg

Inactive Ingredients (Fillers)

⚠️ 4 ingredients flagged as common allergens

Mannitol

⚠️ Yes — Mannitol

Filler/Sweetener

Polyethylene Glycol 3350

⚠️ Yes — PEG

Coating/Osmotic Agent

Povidone

⚠️ Yes — Povidone

Binder

Propylene Glycol

⚠️ Yes — Propylene Glycol

Solvent/Humectant

Cellulose Acetate

Ferrosoferric Oxide

Colorant

Hypromellose

Coating

Magnesium Stearate

Lubricant

Microcrystalline Cellulose

Filler/Binder

Polyethylene Glycol 400

Solvent/Plasticizer

Polyethylene Glycol 8000

Coating/Binder

Silicon Dioxide

Glidant

Talc

Glidant/Lubricant

Titanium Dioxide

Colorant/Opacifier

Ingredient	Purpose	Common Allergen?	Description
Mannitol	Filler/Sweetener	⚠️ Yes — Mannitol	A sugar alcohol used as a sweetener and bulking agent. Can cause osmotic diarrhea in sensitive individuals.
Polyethylene Glycol 3350	Coating/Osmotic Agent	⚠️ Yes — PEG	A higher-molecular-weight PEG used in tablet coatings and as the active ingredient in osmotic laxatives (MiraLAX). Rare PEG allergies documented.
Povidone	Binder	⚠️ Yes — Povidone	A synthetic polymer used as a binder. Rare sensitivities documented in medical literature.
Propylene Glycol	Solvent/Humectant	⚠️ Yes — Propylene Glycol	An organic compound used as a solvent and humectant. Can cause contact dermatitis in sensitive individuals.
Cellulose Acetate	—	No	—
Ferrosoferric Oxide	Colorant	No	Black iron oxide used as a pigment in tablet coatings and capsule shells. Derived from iron, not from food allergen sources.
Hypromellose	Coating	No	A semisynthetic polymer used for tablet coating. Derived from cellulose.
Magnesium Stearate	Lubricant	No	A lubricant that prevents ingredients from sticking to manufacturing equipment.
Microcrystalline Cellulose	Filler/Binder	No	Refined wood pulp used as a filler and binder. Generally inert and well-tolerated.
Polyethylene Glycol 400	Solvent/Plasticizer	No	A low-molecular-weight PEG used as a solvent and plasticizer in oral and topical formulations. Rare but documented allergic reactions to PEG compounds.
Polyethylene Glycol 8000	Coating/Binder	No	A high-molecular-weight PEG used in tablet coatings and as a binder. Rare PEG allergies have been documented.
Silicon Dioxide	Glidant	No	A mineral (silica) used to improve powder flow during tablet manufacturing. Also called colloidal silicon dioxide.
Talc	Glidant/Lubricant	No	A mineral used to improve powder flow in manufacturing.
Titanium Dioxide	Colorant/Opacifier	No	A white pigment used for coating opacity. Under regulatory review in some countries.

Exclusion Groups

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

🌾Gluten 🔴Alpha-Gal Syndrome 🎨Dyes & Colorants 🍬Polyols (GI)🌱Not Vegan ☪️Halal Concern ✡️Kosher Concern 🥦Not Vegetarian

Dietary & Safety Information

Alpha-Gal Syndrome Risk

1 ingredient may contain mammalian-derived components:

Magnesium Stearate(Possible — Stearates can be plant- or animal-derived (verify source).)

AllergenMaps

Ingredient

Purpose

Common Allergen?