DIPHENHYDRAMINE HYDROCHLORIDE, PHENYLEPHRINE HYDROCHLORIDE 6.25 mg / 2.5 mg

LIQUIDORALChain Drug Consortium, LLCNDC: 68016-137Updated: Mar 2026

Active Ingredients

DIPHENHYDRAMINE HYDROCHLORIDE — 6.25 mg

PHENYLEPHRINE HYDROCHLORIDE — 2.5 mg

Inactive Ingredients (Fillers)

⚠️ 4 ingredients flagged as common allergens

FD&C Blue No. 1

⚠️ Yes — Dye

Colorant

FD&C Red No. 40

⚠️ Yes — Dye

Colorant

Propylene Glycol

⚠️ Yes — Propylene Glycol

Solvent/Humectant

Sodium Benzoate

⚠️ Yes — Sodium Benzoate

Preservative

Acesulfame Potassium

Sweetener

Anhydrous Citric Acid

pH Adjuster/Buffer

Disodium Citrate Sesquihydrate

Buffer

Edetate Disodium

Chelating Agent

Hamamelis Virginiana Top Water

Skin Conditioner

Maltitol

Ingredient	Purpose	Common Allergen?	Description
FD&C Blue No. 1	Colorant	⚠️ Yes — Dye	A synthetic blue dye. Less commonly allergenic than other dyes but reactions are documented.
FD&C Red No. 40	Colorant	⚠️ Yes — Dye	A widely used artificial red dye. Among the most common dye allergens.
Propylene Glycol	Solvent/Humectant	⚠️ Yes — Propylene Glycol	An organic compound used as a solvent and humectant. Can cause contact dermatitis in sensitive individuals.
Sodium Benzoate	Preservative	⚠️ Yes — Sodium Benzoate	A food preservative. Can cause urticaria and exacerbate asthma in sensitive individuals.
Acesulfame Potassium	Sweetener	No	A non-caloric artificial sweetener (Ace-K) approximately 200 times sweeter than sugar. Used to improve taste in oral medications.
Anhydrous Citric Acid	pH Adjuster/Buffer	No	Water-free citric acid used to adjust pH and enhance drug stability. Typically derived from fermentation of corn sugar.
Disodium Citrate Sesquihydrate	Buffer	No	A sodium salt of citric acid used as a buffering agent to maintain pH stability in pharmaceutical solutions.
Edetate Disodium	Chelating Agent	No	Also known as EDTA. Binds metal ions to prevent degradation of active ingredients and preserve product stability.
Hamamelis Virginiana Top Water	Skin Conditioner	No	Witch hazel distillate, a plant-derived astringent used in topical formulations to soothe and tone the skin.
Maltitol	—	No	—

Exclusion Groups

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

🌾Gluten 🔴Alpha-Gal Syndrome 🎨Dyes & Colorants 🍬Polyols (GI)🌱Not Vegan ☪️Halal Concern ✡️Kosher Concern 🥦Not Vegetarian

AllergenMaps

Ingredient

Purpose

Common Allergen?

FD&C Blue No. 1

Colorant

⚠️ Yes — Dye

FD&C Red No. 40

Colorant

⚠️ Yes — Dye

Propylene Glycol

Solvent/Humectant

⚠️ Yes — Propylene Glycol

Sodium Benzoate

Preservative

⚠️ Yes — Sodium Benzoate

Acesulfame Potassium

Sweetener

Anhydrous Citric Acid

pH Adjuster/Buffer

Disodium Citrate Sesquihydrate

Buffer

Edetate Disodium

Chelating Agent

Hamamelis Virginiana Top Water

Skin Conditioner

Maltitol

—