Rufinamide (Rufinamide) 40 mg

SUSPENSIONORALAscend Laboratories, LLCNDC: 67877-673Updated: Mar 2026

Active Ingredient

RUFINAMIDE — 40 mg

Inactive Ingredients (Fillers)

⚠️ 5 ingredients flagged as common allergens

Carboxymethylcellulose Sodium

⚠️ Yes — CMC

Thickener/Stabilizer

Lactose Monohydrate

⚠️ Yes — Dairy

Filler/Binder

Methylparaben

⚠️ Yes — Parabens

Preservative

Propylene Glycol

⚠️ Yes — Propylene Glycol

Solvent/Humectant

Propylparaben

⚠️ Yes — Parabens

Preservative

Anhydrous Citric Acid

pH Adjuster/Buffer

Dimethicone 20

Skin Protectant

Hydroxyethyl Cellulose (140 Mpa.s At 5%)

Hypromellose 2910 (5 Mpa.s)

Coating/Binder

Magnesium Stearate

Lubricant

Microcrystalline Cellulose

Filler/Binder

Orange Peel

Potassium Sorbate

Preservative

Silicon Dioxide

Glidant

Sorbitol

Sweetener/Humectant

Ingredient	Purpose	Common Allergen?	Description
Carboxymethylcellulose Sodium	Thickener/Stabilizer	⚠️ Yes — CMC	A cellulose derivative used as a thickener. Rare CMC reactions reported in medical literature.
Lactose Monohydrate	Filler/Binder	⚠️ Yes — Dairy	A sugar derived from milk. Common allergen for lactose-intolerant individuals and those with dairy allergies.
Methylparaben	Preservative	⚠️ Yes — Parabens	A preservative used to prevent microbial growth. Can cause allergic contact dermatitis in sensitive individuals.
Propylene Glycol	Solvent/Humectant	⚠️ Yes — Propylene Glycol	An organic compound used as a solvent and humectant. Can cause contact dermatitis in sensitive individuals.
Propylparaben	Preservative	⚠️ Yes — Parabens	A paraben preservative used to prevent microbial growth. Can cause contact dermatitis in paraben-sensitive individuals.
Anhydrous Citric Acid	pH Adjuster/Buffer	No	Water-free citric acid used to adjust pH and enhance drug stability. Typically derived from fermentation of corn sugar.
Dimethicone 20	Skin Protectant	No	A silicone-based polymer used as a skin protectant, emollient, and anti-foaming agent in topical formulations.
Hydroxyethyl Cellulose (140 Mpa.s At 5%)	—	No	—
Hypromellose 2910 (5 Mpa.s)	Coating/Binder	No	A specific viscosity grade of hydroxypropyl methylcellulose (HPMC) used for film coating and binding. Plant-derived cellulose polymer.
Magnesium Stearate	Lubricant	No	A lubricant that prevents ingredients from sticking to manufacturing equipment.
Microcrystalline Cellulose	Filler/Binder	No	Refined wood pulp used as a filler and binder. Generally inert and well-tolerated.
Orange Peel	—	No	—
Potassium Sorbate	Preservative	No	A potassium salt of sorbic acid used to inhibit mold and yeast growth in pharmaceutical formulations.
Silicon Dioxide	Glidant	No	A mineral (silica) used to improve powder flow during tablet manufacturing. Also called colloidal silicon dioxide.
Sorbitol	Sweetener/Humectant	No	A sugar alcohol used as a sweetener and humectant. Can cause gastrointestinal symptoms (bloating, diarrhea) in sensitive individuals or at high doses. Relevant for those following a low-FODMAP diet.

Exclusion Groups

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

🌾Gluten 🔴Alpha-Gal Syndrome 🥛Milk / Lactose 🍬Polyols (GI)🌱Not Vegan ☪️Halal Concern ✡️Kosher Concern 🥦Not Vegetarian

Dietary & Safety Information

Alpha-Gal Syndrome Risk

2 ingredients may contain mammalian-derived components:

Lactose Monohydrate(Possible — May be mammalian-derived; some alpha-gal patients react (verify source).)
Magnesium Stearate(Possible — Stearates can be plant- or animal-derived (verify source).)