Diphenhydramine Hydrochloride 25 mg

Generic for DIPHENHYDRAMINE HYDROCHLORIDE

CAPSULE, LIQUID FILLEDORALCDMA IncNDC: 63868-474Updated: Mar 2026

Active Ingredient

⚠️ 2 ingredients flagged as common allergens

Gelatin

⚠️ Yes — Animal

Capsule Shell

Derived from animal collagen. Used in capsule shells. Not suitable for vegetarians/vegans or those with specific animal protein sensitivities.

Povidone

⚠️ Yes — Povidone

Binder

A synthetic polymer used as a binder. Rare sensitivities documented in medical literature.

Glycerin

Humectant/Solvent

Hamamelis Virginiana Top Water

Skin Conditioner

Sorbitan

Emulsifier Base

Sorbitol

Sweetener/Humectant

Vitamin E Polyethylene Glycol Succinate?

Solubilizer/Emulsifier

Ingredient	Purpose	Common Allergen?	Description
Gelatin	Capsule Shell	⚠️ Yes — Animal	Derived from animal collagen. Used in capsule shells. Not suitable for vegetarians/vegans or those with specific animal protein sensitivities.
Povidone	Binder	⚠️ Yes — Povidone	A synthetic polymer used as a binder. Rare sensitivities documented in medical literature.
Glycerin	Humectant/Solvent	No	A sugar alcohol that attracts moisture. Used as a humectant, solvent, and sweetener in many oral and topical medications. Generally well tolerated.
Hamamelis Virginiana Top Water	Skin Conditioner	No	Witch hazel distillate, a plant-derived astringent used in topical formulations to soothe and tone the skin.
Sorbitan	Emulsifier Base	No	A cyclic dehydration product of sorbitol, used as a base for making sorbitan ester emulsifiers.
Sorbitol	Sweetener/Humectant	No	A sugar alcohol used as a sweetener and humectant. Can cause gastrointestinal symptoms (bloating, diarrhea) in sensitive individuals or at high doses. Relevant for those following a low-FODMAP diet.
Vitamin E Polyethylene Glycol Succinate?	Solubilizer/Emulsifier	No	A water-soluble form of vitamin E (also called TPGS) used to improve the absorption of poorly soluble drugs. Contains a PEG component.