Spironolactone 25 mg

Generic for SPIRONOLACTONE

TABLET, FILM COATEDORALDirect_RxNDC: 61919-772Updated: Mar 2026

Active Ingredient

SPIRONOLACTONE — 25 mg

Inactive Ingredients (Fillers)

⚠️ 2 ingredients flagged as common allergens

Lactose Monohydrate

⚠️ Yes — Dairy

Filler/Binder

Povidone K25

⚠️ Yes — Povidone

Dibasic Calcium Phosphate Dihydrate

Filler/Binder

Ferric Oxide Yellow

Colorant

Hypromellose

Coating

Magnesium Stearate

Lubricant

Peppermint Oil

Flavoring Agent

Polyethylene Glycol 400

Solvent/Plasticizer

Silicon Dioxide

Glidant

Starch, Corn

Disintegrant/Filler

Talc

Glidant/Lubricant

Titanium Dioxide

Colorant/Opacifier

Ingredient	Purpose	Common Allergen?	Description
Lactose Monohydrate	Filler/Binder	⚠️ Yes — Dairy	A sugar derived from milk. Common allergen for lactose-intolerant individuals and those with dairy allergies.
Povidone K25	—	⚠️ Yes — Povidone	—
Dibasic Calcium Phosphate Dihydrate	Filler/Binder	No	A hydrated calcium phosphate salt used as a filler and binder in tablets. Also provides a source of calcium.
Ferric Oxide Yellow	Colorant	No	Yellow iron oxide pigment used in tablet coatings and capsule shells. A mineral-based colorant.
Hypromellose	Coating	No	A semisynthetic polymer used for tablet coating. Derived from cellulose.
Magnesium Stearate	Lubricant	No	A lubricant that prevents ingredients from sticking to manufacturing equipment.
Peppermint Oil	Flavoring Agent	No	A natural essential oil used as a flavoring and cooling agent. Contains menthol. May cause sensitivity in individuals with mint allergy.
Polyethylene Glycol 400	Solvent/Plasticizer	No	A low-molecular-weight PEG used as a solvent and plasticizer in oral and topical formulations. Rare but documented allergic reactions to PEG compounds.
Silicon Dioxide	Glidant	No	A mineral (silica) used to improve powder flow during tablet manufacturing. Also called colloidal silicon dioxide.
Starch, Corn	Disintegrant/Filler	No	Corn-derived starch used as a filler, binder, or disintegrant. May affect individuals with corn allergy or sensitivity.
Talc	Glidant/Lubricant	No	A mineral used to improve powder flow in manufacturing.
Titanium Dioxide	Colorant/Opacifier	No	A white pigment used for coating opacity. Under regulatory review in some countries.

Exclusion Groups

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

🌾Gluten 🔴Alpha-Gal Syndrome 🥛Milk / Lactose 🎨Dyes & Colorants 🌱Not Vegan ☪️Halal Concern ✡️Kosher Concern 🥦Not Vegetarian

Dietary & Safety Information

Cross-Contamination Risk (source-dependent)

1 ingredient may have cross-contamination risk with gluten (source-dependent):

Starch, Corn — May contain (source-dependent)

Alpha-Gal Syndrome Risk

2 ingredients may contain mammalian-derived components:

Magnesium Stearate(Possible — Stearates can be plant- or animal-derived (verify source).)
Lactose Monohydrate(Possible — May be mammalian-derived; some alpha-gal patients react (verify source).)

AllergenMaps

Ingredient

Purpose

Common Allergen?

Lactose Monohydrate

Filler/Binder

⚠️ Yes — Dairy

Povidone K25

—

⚠️ Yes — Povidone

Dibasic Calcium Phosphate Dihydrate

Filler/Binder

Ferric Oxide Yellow

Colorant

Hypromellose

Coating

Magnesium Stearate

Lubricant

Peppermint Oil

Flavoring Agent

Polyethylene Glycol 400

Solvent/Plasticizer

Silicon Dioxide

Glidant

Starch, Corn

Disintegrant/Filler

Talc

Glidant/Lubricant

Titanium Dioxide

Colorant/Opacifier

Dietary & Safety Information

Cross-Contamination Risk (source-dependent)

1 ingredient may have cross-contamination risk with gluten (source-dependent):

Starch, Corn — May contain (source-dependent)

Alpha-Gal Syndrome Risk

2 ingredients may contain mammalian-derived components:

Magnesium Stearate(Possible — Stearates can be plant- or animal-derived (verify source).)
Lactose Monohydrate(Possible — May be mammalian-derived; some alpha-gal patients react (verify source).)