Bijuva (estradiol and progesterone) 0.5 mg / 100 mg

CAPSULEORALMayne Pharma LLCNDC: 50261-251Updated: Mar 2026

Active Ingredients

ESTRADIOL — 0.5 mg

PROGESTERONE — 100 mg

Inactive Ingredients (Fillers)

⚠️ 6 ingredients flagged as common allergens

Alcohol

⚠️ Yes — Alcohol

Solvent/Preservative

FD&C Red No. 40

⚠️ Yes — Dye

Colorant

Gelatin

⚠️ Yes — Animal

Capsule Shell

Lauroyl PEG-32 Glycerides

⚠️ Yes — PEG

Medium-chain Triglycerides

⚠️ Yes — Coconut

Solvent/Vehicle

Propylene Glycol

⚠️ Yes — Propylene Glycol

Solvent/Humectant

Ammonia Solution

pH Adjuster

Ethyl Acetate

Glycerin

Humectant/Solvent

Glyceryl Mono- And Dicaprylocaprate

Emulsifier/Penetration Enhancer

Hamamelis Virginiana Top Water

Skin Conditioner

Isopropyl Alcohol

Solvent/Antiseptic

Polyvinyl Acetate Phthalate

Soybean Lecithin

Emulsifier

Titanium Dioxide

Colorant/Opacifier

Vitamin E Polyethylene Glycol Succinate?

Solubilizer/Emulsifier

Ingredient	Purpose	Common Allergen?	Description
Alcohol	Solvent/Preservative	⚠️ Yes — Alcohol	Ethanol (ethyl alcohol) used as a solvent, preservative, or extraction agent. Present in many liquid formulations. May be relevant for patients avoiding alcohol for medical or religious reasons.
FD&C Red No. 40	Colorant	⚠️ Yes — Dye	A widely used artificial red dye. Among the most common dye allergens.
Gelatin	Capsule Shell	⚠️ Yes — Animal	Derived from animal collagen. Used in capsule shells. Not suitable for vegetarians/vegans or those with specific animal protein sensitivities.
Lauroyl PEG-32 Glycerides	—	⚠️ Yes — PEG	—
Medium-chain Triglycerides	Solvent/Vehicle	⚠️ Yes — Coconut	Fatty acid esters derived from coconut or palm kernel oil. Used as a solvent and vehicle in oral and topical formulations. May be relevant for individuals with coconut sensitivity.
Propylene Glycol	Solvent/Humectant	⚠️ Yes — Propylene Glycol	An organic compound used as a solvent and humectant. Can cause contact dermatitis in sensitive individuals.
Ammonia Solution	pH Adjuster	No	Dilute ammonia used to adjust pH in pharmaceutical formulations. Present in trace amounts in the final product.
Ethyl Acetate	—	No	—
Glycerin	Humectant/Solvent	No	A sugar alcohol that attracts moisture. Used as a humectant, solvent, and sweetener in many oral and topical medications. Generally well tolerated.
Glyceryl Mono- And Dicaprylocaprate	Emulsifier/Penetration Enhancer	No	Mixed glyceride esters used as emulsifiers and to enhance drug absorption through the skin.
Hamamelis Virginiana Top Water	Skin Conditioner	No	Witch hazel distillate, a plant-derived astringent used in topical formulations to soothe and tone the skin.
Isopropyl Alcohol	Solvent/Antiseptic	No	Rubbing alcohol. Used as a solvent in topical formulations and as an antiseptic agent.
Polyvinyl Acetate Phthalate	—	No	—
Soybean Lecithin	Emulsifier	No	A phospholipid mixture extracted from soybeans, used as an emulsifier and wetting agent. Derived from soy — must be avoided by individuals with soy allergy.
Titanium Dioxide	Colorant/Opacifier	No	A white pigment used for coating opacity. Under regulatory review in some countries.
Vitamin E Polyethylene Glycol Succinate?	Solubilizer/Emulsifier	No	A water-soluble form of vitamin E (also called TPGS) used to improve the absorption of poorly soluble drugs. Contains a PEG component.

Exclusion Groups

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

🔴Alpha-Gal Syndrome 🫘Soy 🥜Peanut / Tree Nut 🎨Dyes & Colorants 🌱Not Vegan ☪️Halal Concern ✡️Kosher Concern 🥦Not Vegetarian

Dietary & Safety Information

Alpha-Gal Syndrome Risk

2 ingredients may contain mammalian-derived components:

Gelatin(Yes — Mammalian-derived – alpha-gal risk (verify processing/source).)
Glycerin(Possible — Glycerin can be plant- or animal-derived (verify source).)

AllergenMaps

Ingredient

Purpose

Common Allergen?