Diphenhydramine HCl 12.5 mg

LIQUIDORALA-S Medication SolutionsNDC: 50090-2935Updated: Mar 2026

Active Ingredient

DIPHENHYDRAMINE HYDROCHLORIDE — 12.5 mg

Inactive Ingredients (Fillers)

⚠️ 3 ingredients flagged as common allergens

FD&C Red No. 40

⚠️ Yes — Dye

Colorant

A widely used artificial red dye. Among the most common dye allergens.

Saccharin Sodium

⚠️ Yes — Saccharin

Sweetener

An artificial sweetener. Rare sensitivities reported, including skin reactions.

Sodium Benzoate

⚠️ Yes — Sodium Benzoate

Preservative

A food preservative. Can cause urticaria and exacerbate asthma in sensitive individuals.

Anhydrous Citric Acid

pH Adjuster/Buffer

Cherry

D&C Red No. 33

Colorant

Disodium Citrate Sesquihydrate?

Buffer

Glycerin

Humectant/Solvent

Hamamelis Virginiana Top Water

Skin Conditioner

Polysorbate 20

Emulsifier/Solubilizer

Sorbitol

Sweetener/Humectant

Ingredient	Purpose	Common Allergen?	Description
FD&C Red No. 40	Colorant	⚠️ Yes — Dye	A widely used artificial red dye. Among the most common dye allergens.
Saccharin Sodium	Sweetener	⚠️ Yes — Saccharin	An artificial sweetener. Rare sensitivities reported, including skin reactions.
Sodium Benzoate	Preservative	⚠️ Yes — Sodium Benzoate	A food preservative. Can cause urticaria and exacerbate asthma in sensitive individuals.
Anhydrous Citric Acid	pH Adjuster/Buffer	No	Water-free citric acid used to adjust pH and enhance drug stability. Typically derived from fermentation of corn sugar.
Cherry	—	No	—
D&C Red No. 33	Colorant	No	A synthetic red dye used in topical formulations and some oral medications. May cause reactions in individuals with dye sensitivities.
Disodium Citrate Sesquihydrate?	Buffer	No	A sodium salt of citric acid used as a buffering agent to maintain pH stability in pharmaceutical solutions.
Glycerin	Humectant/Solvent	No	A sugar alcohol that attracts moisture. Used as a humectant, solvent, and sweetener in many oral and topical medications. Generally well tolerated.
Hamamelis Virginiana Top Water	Skin Conditioner	No	Witch hazel distillate, a plant-derived astringent used in topical formulations to soothe and tone the skin.
Polysorbate 20	Emulsifier/Solubilizer	No	A non-ionic surfactant similar to polysorbate 80 but derived from lauric acid. Used to solubilize and stabilize formulations.
Sorbitol	Sweetener/Humectant	No	A sugar alcohol used as a sweetener and humectant. Can cause gastrointestinal symptoms (bloating, diarrhea) in sensitive individuals or at high doses. Relevant for those following a low-FODMAP diet.