Juluca (dolutegravir sodium and rilpivirine hydrochloride) 50 mg / 25 mg

TABLET, FILM COATEDORALViiV Healthcare CompanyNDC: 49702-242Updated: Mar 2026

Active Ingredients

DOLUTEGRAVIR SODIUM — 50 mg

RILPIVIRINE HYDROCHLORIDE — 25 mg

Inactive Ingredients (Fillers)

⚠️ 3 ingredients flagged as common allergens

Lactose Monohydrate

⚠️ Yes — Dairy

Filler/Binder

Mannitol

⚠️ Yes — Mannitol

Filler/Sweetener

Povidone K30

⚠️ Yes — Povidone

Binder

Croscarmellose Sodium

Disintegrant

Microcrystalline Cellulose

Filler/Binder

Polysorbate 20

Emulsifier/Solubilizer

Sodium Starch Glycolate Type A

Disintegrant

Sodium Stearyl Fumarate

Lubricant

Ingredient	Purpose	Common Allergen?	Description
Lactose Monohydrate	Filler/Binder	⚠️ Yes — Dairy	A sugar derived from milk. Common allergen for lactose-intolerant individuals and those with dairy allergies.
Mannitol	Filler/Sweetener	⚠️ Yes — Mannitol	A sugar alcohol used as a sweetener and bulking agent. Can cause osmotic diarrhea in sensitive individuals.
Povidone K30	Binder	⚠️ Yes — Povidone	A grade of polyvinylpyrrolidone (PVP) used as a binder in tablet manufacturing. The K30 denotes a specific molecular weight range.
Croscarmellose Sodium	Disintegrant	No	A chemically modified cellulose derivative that helps tablets dissolve quickly.
Microcrystalline Cellulose	Filler/Binder	No	Refined wood pulp used as a filler and binder. Generally inert and well-tolerated.
Polysorbate 20	Emulsifier/Solubilizer	No	A non-ionic surfactant similar to polysorbate 80 but derived from lauric acid. Used to solubilize and stabilize formulations.
Sodium Starch Glycolate Type A	Disintegrant	No	A modified starch (typically potato-derived) that swells rapidly in water, helping tablets break apart for faster drug release.
Sodium Stearyl Fumarate	Lubricant	No	A tablet lubricant used as an alternative to magnesium stearate. Vegetable-derived.

Exclusion Groups

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

🌾Gluten 🔴Alpha-Gal Syndrome 🥛Milk / Lactose 🍬Polyols (GI)🌱Not Vegan ☪️Halal Concern ✡️Kosher Concern 🥦Not Vegetarian

Dietary & Safety Information

Cross-Contamination Risk (source-dependent)

1 ingredient may have cross-contamination risk with gluten (source-dependent):

Sodium Starch Glycolate Type A — May contain (source-dependent)

Alpha-Gal Syndrome Risk

1 ingredient may contain mammalian-derived components:

Lactose Monohydrate(Possible — May be mammalian-derived; some alpha-gal patients react (verify source).)

AllergenMaps

Ingredient

Purpose

Common Allergen?

Lactose Monohydrate

Filler/Binder

⚠️ Yes — Dairy

Mannitol

Filler/Sweetener

⚠️ Yes — Mannitol

Povidone K30

Binder

⚠️ Yes — Povidone

Croscarmellose Sodium

Disintegrant

Microcrystalline Cellulose

Filler/Binder

Polysorbate 20

Emulsifier/Solubilizer

Sodium Starch Glycolate Type A

Disintegrant

Sodium Stearyl Fumarate

Lubricant

Dietary & Safety Information

Cross-Contamination Risk (source-dependent)

1 ingredient may have cross-contamination risk with gluten (source-dependent):

Sodium Starch Glycolate Type A — May contain (source-dependent)

Alpha-Gal Syndrome Risk

1 ingredient may contain mammalian-derived components:

Lactose Monohydrate(Possible — May be mammalian-derived; some alpha-gal patients react (verify source).)