Acetaminophen, Diphenhydramine HCl, Phenylephrine HCl 650 mg / 25 mg / 10 mg

Generic for THERAFLU EXPRESSMAX NIGHTTIME SEVERE COLD AND COUGH

TABLET, EFFERVESCENTORALAdvanced Pharmaceutical Services, Inc. Dba Affordable Quality PharmaceuticalsNDC: 13411-841Updated: Mar 2026

Active Ingredients

ACETAMINOPHEN — 650 mg

DIPHENHYDRAMINE HYDROCHLORIDE — 25 mg

PHENYLEPHRINE HYDROCHLORIDE — 10 mg

Inactive Ingredients (Fillers)

⚠️ 3 ingredients flagged as common allergens

Aspartame

⚠️ Yes — Aspartame

Sweetener

An artificial sweetener. Dangerous for individuals with phenylketonuria (PKU). Rare general sensitivities reported.

Mannitol

⚠️ Yes — Mannitol

Filler/Sweetener

A sugar alcohol used as a sweetener and bulking agent. Can cause osmotic diarrhea in sensitive individuals.

Povidone K30

⚠️ Yes — Povidone

Binder

A grade of polyvinylpyrrolidone (PVP) used as a binder in tablet manufacturing. The K30 denotes a specific molecular weight range.

Anhydrous Citric Acid

pH Adjuster/Buffer

Dimethicone 20

Skin Protectant

Disodium Citrate Sesquihydrate

Buffer

Polysorbate 20

Emulsifier/Solubilizer

Sodium Bicarbonate

Buffer/Effervescent Agent

Sodium Carbonate

pH Adjuster/Buffer

Vitamin E Polyethylene Glycol Succinate?

Solubilizer/Emulsifier

Ingredient	Purpose	Common Allergen?	Description
Aspartame	Sweetener	⚠️ Yes — Aspartame	An artificial sweetener. Dangerous for individuals with phenylketonuria (PKU). Rare general sensitivities reported.
Mannitol	Filler/Sweetener	⚠️ Yes — Mannitol	A sugar alcohol used as a sweetener and bulking agent. Can cause osmotic diarrhea in sensitive individuals.
Povidone K30	Binder	⚠️ Yes — Povidone	A grade of polyvinylpyrrolidone (PVP) used as a binder in tablet manufacturing. The K30 denotes a specific molecular weight range.
Anhydrous Citric Acid	pH Adjuster/Buffer	No	Water-free citric acid used to adjust pH and enhance drug stability. Typically derived from fermentation of corn sugar.
Dimethicone 20	Skin Protectant	No	A silicone-based polymer used as a skin protectant, emollient, and anti-foaming agent in topical formulations.
Disodium Citrate Sesquihydrate	Buffer	No	A sodium salt of citric acid used as a buffering agent to maintain pH stability in pharmaceutical solutions.
Polysorbate 20	Emulsifier/Solubilizer	No	A non-ionic surfactant similar to polysorbate 80 but derived from lauric acid. Used to solubilize and stabilize formulations.
Sodium Bicarbonate	Buffer/Effervescent Agent	No	Baking soda. Used as a buffering agent, antacid, or effervescent component in tablets and solutions.
Sodium Carbonate	pH Adjuster/Buffer	No	Washing soda. Used as an alkalizing agent and buffering agent in pharmaceutical formulations.
Vitamin E Polyethylene Glycol Succinate?	Solubilizer/Emulsifier	No	A water-soluble form of vitamin E (also called TPGS) used to improve the absorption of poorly soluble drugs. Contains a PEG component.