| Cetyl Alcohol? | Emulsifier/Thickener | ?Uncertain — Cetyl Alcohol | A fatty alcohol used in topical formulations. Can cause contact dermatitis. |
| Medium-chain Triglycerides | Solvent/Vehicle | ⚠️ Yes — Coconut | Fatty acid esters derived from coconut or palm kernel oil. Used as a solvent and vehicle in oral and topical formulations. May be relevant for individuals with coconut sensitivity. |
| PEG-20 Sorbitan Isostearate | Emulsifier | ⚠️ Yes — PEG | A PEG-modified sorbitan ester used as a non-ionic emulsifier in topical formulations. |
| Peg/ppg-18/18 Dimethicone | Emulsifier/Skin Conditioner | ⚠️ Yes — PEG | A silicone-based emulsifier combining PEG and polypropylene glycol with dimethicone. Used in topical formulations for smooth application. |
| Sodium Benzoate | Preservative | ⚠️ Yes — Sodium Benzoate | A food preservative. Can cause urticaria and exacerbate asthma in sensitive individuals. |
| Sodium Metabisulfite | Antioxidant/Preservative | ⚠️ Yes — Sulfite | A sulfite compound used as an antioxidant and preservative. Can trigger severe reactions (bronchospasm, anaphylaxis) in sulfite-sensitive individuals, particularly asthmatics. |
| .alpha.-tocopherol Acetate | Antioxidant | No | Vitamin E acetate. Used as an antioxidant to protect active ingredients from degradation during storage. |
| Acrylic Acid-2-ethylhexyl Acrylate-2-hydroxyethyl Acrylate-vinyl Acetate Copolymer (for Duro-tak 87-2070)? | Adhesive | No | A pressure-sensitive adhesive polymer used in transdermal patches to hold the patch to the skin. |
| Algeldrate? | Antacid | No | Aluminum hydroxide gel. Used as an antacid and in some vaccine formulations as an adjuvant. |
| Aluminum Hydroxide | Antacid/Adjuvant | No | An aluminum salt used as an antacid ingredient and as an adjuvant in some vaccine formulations. |
| Ascorbyl Palmitate | Antioxidant | No | A fat-soluble form of vitamin C used as an antioxidant in pharmaceutical formulations to prevent oxidation of fats and oils. |
| Butylated Hydroxytoluene | Antioxidant | No | BHT. A synthetic antioxidant used to prevent oxidative degradation of fats and oils in pharmaceutical products. Rare contact sensitivity reported. |
| Butylene Glycol | Humectant/Solvent | No | A synthetic glycol used as a humectant and solvent in topical formulations. Helps products spread smoothly on skin. |
| Calcium Chloride Anhydrous? | — | No | — |
| Carbon Dioxide? | Propellant/Preservative | No | Used as a propellant in aerosol products and to displace oxygen in packaging to preserve product stability. |
| Chloroxylenol | — | No | — |
| Cholesterol | Emulsifier/Stabilizer | No | A natural lipid used as an emulsifier and stabilizer in liposomal and topical formulations. Typically derived from animal sources (lanolin). |
| Dimethicone 20 | Skin Protectant | No | A silicone-based polymer used as a skin protectant, emollient, and anti-foaming agent in topical formulations. |
| Dimethicone 200? | Skin Protectant/Emollient | No | A specific viscosity grade of dimethicone (polydimethylsiloxane). Used as a skin protectant, emollient, and anti-foaming agent. |
| Dipalmitoylphosphatidylglycerol, Dl-? | Surfactant/Stabilizer | No | A synthetic phospholipid used as a lung surfactant component and stabilizer in inhaled formulations. |
| Ethylhexyl Hydroxystearate? | Emollient | No | A synthetic ester used as an emollient and skin-conditioning agent in topical formulations. |
| Ferric Oxide Red | Colorant | No | Red iron oxide pigment used in tablet coatings and capsule shells. A mineral-based colorant, distinct from FD&C synthetic dyes. |
| Ferric Oxide Yellow | Colorant | No | Yellow iron oxide pigment used in tablet coatings and capsule shells. A mineral-based colorant. |
| Ferrosoferric Oxide | Colorant | No | Black iron oxide used as a pigment in tablet coatings and capsule shells. Derived from iron, not from food allergen sources. |
| Glycerin | Humectant/Solvent | No | A sugar alcohol that attracts moisture. Used as a humectant, solvent, and sweetener in many oral and topical medications. Generally well tolerated. |
| Hamamelis Virginiana Top Water | Skin Conditioner | No | Witch hazel distillate, a plant-derived astringent used in topical formulations to soothe and tone the skin. |
| Hyaluronate Sodium | Moisturizer/Viscosity Agent | No | Sodium hyaluronic acid. A naturally occurring substance used as a moisturizer and viscosity agent in ophthalmic and topical formulations. |
| Hydrogenated Soybean Lecithin | Emulsifier | No | A hydrogenated form of soy lecithin used as an emulsifier and stabilizer. Derived from soy — must be avoided by individuals with soy allergy. |
| Laureth-2 | Emulsifier/Solubilizer | No | A non-ionic surfactant used as an emulsifier and solubilizer in topical formulations. |
| Magnesium Carbonate? | Antacid/Adsorbent | No | A magnesium salt used as an antacid and adsorbent. Also used as a drying agent in tablet manufacturing. |
| Magnesium Sulfate | Osmotic Agent | No | Epsom salt. Used as an osmotic agent, drying agent, and in injectable formulations for electrolyte supplementation. |
| Methacrylic Acid - Methyl Methacrylate Copolymer (1:1)? | Enteric Coating | No | An acrylic polymer (Eudragit L100) used for enteric coating that dissolves in the intestine rather than the stomach. |
| Methionine? | — | No | — |
| Microcrystalline Wax? | Stiffening Agent | No | A petroleum-derived wax used to adjust consistency in ointments and as a coating agent. |
| Phenoxyethanol | Preservative | No | A synthetic preservative used to prevent microbial growth in topical and some oral formulations. Can cause skin irritation in sensitive individuals. |
| Pineapple | — | No | — |
| Potassium Sorbate | Preservative | No | A potassium salt of sorbic acid used to inhibit mold and yeast growth in pharmaceutical formulations. |
| Propylene Carbonate | Solvent | No | An organic solvent used in transdermal patches and topical formulations to dissolve active ingredients. |
| Ricinoleic Acid | — | No | — |
| Sodium Lactate | — | No | — |
| Sodium Phosphate, Monobasic? | Buffer | No | A phosphate salt used as a buffering agent to maintain acidic pH in pharmaceutical solutions. |
| Sodium Pyrrolidone Carboxylate | Humectant | No | Sodium PCA. A natural moisturizing factor component used as a humectant in topical formulations. |
| Sorbic Acid | Preservative | No | An antimicrobial preservative used to inhibit mold and yeast growth. Generally well tolerated. |
| Sorbitan Monostearate | Emulsifier | No | A non-ionic surfactant (Span 60) used to stabilize emulsions in creams, ointments, and oral formulations. |
| Sorbitan Sesquioleate | — | No | — |
| Stearalkonium Chloride? | Conditioning Agent | No | A quaternary ammonium compound used as a conditioning and antistatic agent in topical formulations. |
| Stearic Acid | Lubricant | No | A fatty acid used as a lubricant in tablet manufacturing. |
| Tocopherol | Antioxidant | No | Natural vitamin E. Used as an antioxidant to protect active ingredients from oxidation and extend product shelf life. |
| Triacetin? | Plasticizer | No | Glyceryl triacetate. A plasticizer used in film coatings to make them flexible and prevent cracking. |
| Triethyl Citrate | Plasticizer | No | A citric acid ester used as a plasticizer in enteric coatings and controlled-release formulations. |
| Xanthan Gum | Thickener/Stabilizer | No | A polysaccharide produced by bacterial fermentation, used to thicken and stabilize liquid and semi-solid formulations. Derived from corn sugar fermentation — may be relevant for corn-sensitive individuals. |