Acetaminophen (Acetaminophen) 325 mg

SOLUTIONORALMajor PharmaceuticalsNDC: 0904-7320Updated: Mar 2026

Active Ingredient

ACETAMINOPHEN — 325 mg

Inactive Ingredients (Fillers)

⚠️ 4 ingredients flagged as common allergens

FD&C Red No. 40

⚠️ Yes — Dye

Colorant

Propylene Glycol

⚠️ Yes — Propylene Glycol

Solvent/Humectant

Sodium Benzoate

⚠️ Yes — Sodium Benzoate

Preservative

Sucrose

⚠️ Yes — Sucrose

Sweetener/Coating

Anhydrous Citric Acid

pH Adjuster/Buffer

Disodium Citrate Sesquihydrate

Buffer

Glycerin

Humectant/Solvent

Hamamelis Virginiana Top Water

Skin Conditioner

Sorbitol

Sweetener/Humectant

Vitamin E Polyethylene Glycol Succinate?

Solubilizer/Emulsifier

Ingredient	Purpose	Common Allergen?	Description
FD&C Red No. 40	Colorant	⚠️ Yes — Dye	A widely used artificial red dye. Among the most common dye allergens.
Propylene Glycol	Solvent/Humectant	⚠️ Yes — Propylene Glycol	An organic compound used as a solvent and humectant. Can cause contact dermatitis in sensitive individuals.
Sodium Benzoate	Preservative	⚠️ Yes — Sodium Benzoate	A food preservative. Can cause urticaria and exacerbate asthma in sensitive individuals.
Sucrose	Sweetener/Coating	⚠️ Yes — Sucrose	Common table sugar. Problematic for individuals with sucrose intolerance or congenital sucrase-isomaltase deficiency.
Anhydrous Citric Acid	pH Adjuster/Buffer	No	Water-free citric acid used to adjust pH and enhance drug stability. Typically derived from fermentation of corn sugar.
Disodium Citrate Sesquihydrate	Buffer	No	A sodium salt of citric acid used as a buffering agent to maintain pH stability in pharmaceutical solutions.
Glycerin	Humectant/Solvent	No	A sugar alcohol that attracts moisture. Used as a humectant, solvent, and sweetener in many oral and topical medications. Generally well tolerated.
Hamamelis Virginiana Top Water	Skin Conditioner	No	Witch hazel distillate, a plant-derived astringent used in topical formulations to soothe and tone the skin.
Sorbitol	Sweetener/Humectant	No	A sugar alcohol used as a sweetener and humectant. Can cause gastrointestinal symptoms (bloating, diarrhea) in sensitive individuals or at high doses. Relevant for those following a low-FODMAP diet.
Vitamin E Polyethylene Glycol Succinate?	Solubilizer/Emulsifier	No	A water-soluble form of vitamin E (also called TPGS) used to improve the absorption of poorly soluble drugs. Contains a PEG component.