ADVIL PM (diphenhydramine HCl, ibuprofen) 25 mg / 200 mg

CAPSULE, LIQUID FILLEDORALHaleon US Holdings LLCNDC: 0573-0167Updated: Mar 2026

Active Ingredients

DIPHENHYDRAMINE HYDROCHLORIDE — 25 mg

IBUPROFEN — 200 mg

Inactive Ingredients (Fillers)

⚠️ 3 ingredients flagged as common allergens

FD&C Blue No. 1

⚠️ Yes — Dye

Colorant

A synthetic blue dye. Less commonly allergenic than other dyes but reactions are documented.

Gelatin

⚠️ Yes — Animal

Capsule Shell

Derived from animal collagen. Used in capsule shells. Not suitable for vegetarians/vegans or those with specific animal protein sensitivities.

Medium-chain Triglycerides

⚠️ Yes — Coconut

Solvent/Vehicle

Fatty acid esters derived from coconut or palm kernel oil. Used as a solvent and vehicle in oral and topical formulations. May be relevant for individuals with coconut sensitivity.

D&C Red No. 33

Colorant

Hamamelis Virginiana Top Water

Skin Conditioner

Potassium Hydroxide

pH Adjuster

Sorbitan

Emulsifier Base

Sorbitol

Sweetener/Humectant

Vitamin E Polyethylene Glycol Succinate?

Solubilizer/Emulsifier

Ingredient	Purpose	Common Allergen?	Description
FD&C Blue No. 1	Colorant	⚠️ Yes — Dye	A synthetic blue dye. Less commonly allergenic than other dyes but reactions are documented.
Gelatin	Capsule Shell	⚠️ Yes — Animal	Derived from animal collagen. Used in capsule shells. Not suitable for vegetarians/vegans or those with specific animal protein sensitivities.
Medium-chain Triglycerides	Solvent/Vehicle	⚠️ Yes — Coconut	Fatty acid esters derived from coconut or palm kernel oil. Used as a solvent and vehicle in oral and topical formulations. May be relevant for individuals with coconut sensitivity.
D&C Red No. 33	Colorant	No	A synthetic red dye used in topical formulations and some oral medications. May cause reactions in individuals with dye sensitivities.
Hamamelis Virginiana Top Water	Skin Conditioner	No	Witch hazel distillate, a plant-derived astringent used in topical formulations to soothe and tone the skin.
Potassium Hydroxide	pH Adjuster	No	A strong alkali used to adjust pH in pharmaceutical formulations. Present only in trace amounts in the final product.
Sorbitan	Emulsifier Base	No	A cyclic dehydration product of sorbitol, used as a base for making sorbitan ester emulsifiers.
Sorbitol	Sweetener/Humectant	No	A sugar alcohol used as a sweetener and humectant. Can cause gastrointestinal symptoms (bloating, diarrhea) in sensitive individuals or at high doses. Relevant for those following a low-FODMAP diet.
Vitamin E Polyethylene Glycol Succinate?	Solubilizer/Emulsifier	No	A water-soluble form of vitamin E (also called TPGS) used to improve the absorption of poorly soluble drugs. Contains a PEG component.