SCEMBLIX (asciminib) 40 mg

TABLET, FILM COATEDORALNovartis Pharmaceuticals CorporationNDC: 0078-1098Updated: Mar 2026

Active Ingredient

ASCIMINIB HYDROCHLORIDE — 40 mg

Inactive Ingredients (Fillers)

⚠️ 1 ingredient flagged as common allergen

Lactose Monohydrate

⚠️ Yes — Dairy

Filler/Binder

Croscarmellose Sodium

Disintegrant

Ferric Oxide Red

Colorant

Ferrosoferric Oxide

Colorant

Hydroxypropyl Cellulose

Binder/Coating

Magnesium Stearate

Lubricant

Microcrystalline Cellulose

Filler/Binder

Polyvinyl Alcohol

Coating Agent/Stabilizer

Silicon Dioxide

Glidant

Soybean Lecithin

Emulsifier

Talc

Glidant/Lubricant

Titanium Dioxide

Colorant/Opacifier

Xanthan Gum

Thickener/Stabilizer

Ingredient	Purpose	Common Allergen?	Description
Lactose Monohydrate	Filler/Binder	⚠️ Yes — Dairy	A sugar derived from milk. Common allergen for lactose-intolerant individuals and those with dairy allergies.
Croscarmellose Sodium	Disintegrant	No	A chemically modified cellulose derivative that helps tablets dissolve quickly.
Ferric Oxide Red	Colorant	No	Red iron oxide pigment used in tablet coatings and capsule shells. A mineral-based colorant, distinct from FD&C synthetic dyes.
Ferrosoferric Oxide	Colorant	No	Black iron oxide used as a pigment in tablet coatings and capsule shells. Derived from iron, not from food allergen sources.
Hydroxypropyl Cellulose	Binder/Coating	No	A cellulose derivative used as a binder, film-coating agent, and thickener. Plant-derived.
Magnesium Stearate	Lubricant	No	A lubricant that prevents ingredients from sticking to manufacturing equipment.
Microcrystalline Cellulose	Filler/Binder	No	Refined wood pulp used as a filler and binder. Generally inert and well-tolerated.
Polyvinyl Alcohol	Coating Agent/Stabilizer	No	A synthetic polymer used in film coatings for tablets and as a stabilizer in ophthalmic solutions.
Silicon Dioxide	Glidant	No	A mineral (silica) used to improve powder flow during tablet manufacturing. Also called colloidal silicon dioxide.
Soybean Lecithin	Emulsifier	No	A phospholipid mixture extracted from soybeans, used as an emulsifier and wetting agent. Derived from soy — must be avoided by individuals with soy allergy.
Talc	Glidant/Lubricant	No	A mineral used to improve powder flow in manufacturing.
Titanium Dioxide	Colorant/Opacifier	No	A white pigment used for coating opacity. Under regulatory review in some countries.
Xanthan Gum	Thickener/Stabilizer	No	A polysaccharide produced by bacterial fermentation, used to thicken and stabilize liquid and semi-solid formulations. Derived from corn sugar fermentation — may be relevant for corn-sensitive individuals.

Exclusion Groups

This medication contains ingredients flagged in the following groups. Patients with these sensitivities should consult their prescriber.

🔴Alpha-Gal Syndrome 🥛Milk / Lactose 🫘Soy 🎨Dyes & Colorants 🌱Not Vegan ☪️Halal Concern ✡️Kosher Concern 🥦Not Vegetarian

Dietary & Safety Information

Alpha-Gal Syndrome Risk

2 ingredients may contain mammalian-derived components:

Lactose Monohydrate(Possible — May be mammalian-derived; some alpha-gal patients react (verify source).)
Magnesium Stearate(Possible — Stearates can be plant- or animal-derived (verify source).)

AllergenMaps

Ingredient

Purpose

Common Allergen?

Lactose Monohydrate

Filler/Binder

⚠️ Yes — Dairy

Croscarmellose Sodium

Disintegrant

Ferric Oxide Red

Colorant

Ferrosoferric Oxide

Colorant

Hydroxypropyl Cellulose

Binder/Coating

Magnesium Stearate

Lubricant

Microcrystalline Cellulose

Filler/Binder

Polyvinyl Alcohol

Coating Agent/Stabilizer

Silicon Dioxide

Glidant

Soybean Lecithin

Emulsifier

Talc

Glidant/Lubricant

Titanium Dioxide

Colorant/Opacifier

Xanthan Gum

Thickener/Stabilizer