Polyol (sugar alcohol) excipients including sorbitol, mannitol, xylitol, maltitol, and isomalt are used as sweeteners, diluents, and tonicity agents. They can cause dose-dependent GI symptoms due to osmotic effects.
Patients with polyol intolerance, irritable bowel syndrome (IBS), those following a low-FODMAP diet, or individuals sensitive to osmotic laxative effects.
Sugar-free tablets, chewable medications, liquid formulations, and IV solutions (mannitol).
200 medications containing Polyols (GI)
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